By Gerhard Freund (auth.), Milton M. Gross (eds.)
Dr. Milton M. Gross, the editor of those volumes, died on July 29, 1976, after a short affliction. As chairman of the part on Biomedical examine in Alcoholism of the I.C.A.A., he had plan ned and taken to fruition the foreign "Symposium on Alcohol Intoxication and Withdrawal" which had taken position in Lausanne the month ahead of. He was once quite happy with the prestigious team of scientists he had helped to collect and used to be eagerly trying to find ward to the ebook of those court cases which he was hoping could expand our knowing of the phenomenology of alcoholism. Milton Gross was once a most original guy within the quantity and diversity of his actions and accomplishments. He was once a professional psy chiatrist and psychoanalyst, a well-known medical researcher, the writer of greater than fifty medical papers, and the editor of 3 very important volumes on alcohol intoxication and withdrawal. He was once super energetic within the medical international of alcoholism as planner and coordinator of 3 overseas meetings, as chairman of the part on Biomedical learn of the I.C.A.A., and as a member of a W.H.O. activity strength on Alcoholism. moreover, he was once very lively in a number of medical and repair committees in nationwide and native organizations.
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Additional info for Alcohol Intoxication and Withdrawal—IIIb: Studies in Alcohol Dependence
All ... * III( 15~------p------p------~ 12 24 36 CHRONIC TREATMENT (days) Figure 2. Equieffective pentobarbital chronic treatment. Abscissa: number of days of chronic treatment. Ordinate, upper tracing (() ) : the average maximal eNS depression rating recorded daily during the chronic treatment. Ordinate, middle tracing ( . ) : average daily single dose of sodium pentobarbital in mg/kg, administered through the gastric cannula. Ordinate, lower tracing (*): blood pentobarbital concentration during the chronic treatment.
Blood ethanol concentrations (BEC) were analyzed frequently so that the concentration of the infusion solution could be adjusted accordingly if it was found that BEC was gradually increasing or decreasing. In general, such adjustments were made if BEC varied more than + 10% of the intended value. Minor adjustments in BEC could also be achieved by interrupting the infusion for a short, calculated interval or by injecting a small dose of ethanol through the catheter. v. injection of an appropriate dose of ethanol during a 10-15 minute period.
2) Ethanol dependence phase characterized by a spectrum of withdrawal signs and reactions. The successive onset and disappearance of the two sets of signs and reactions during both phases of the ethanol withdrawal period constitute a continuum of effects and responses and represent a reversal in the CNS function from the extremes of ethanol depression to the extremes of hyperexcitability. The importance of the central nervous system in the biobehavioral and clinical components of the ethanol withdrawal syndrome has been generally recognized and consequently will not be discussed here in detail.
Alcohol Intoxication and Withdrawal—IIIb: Studies in Alcohol Dependence by Gerhard Freund (auth.), Milton M. Gross (eds.)