Download e-book for kindle: An introduction to vascular biology : from basic science to by Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison

By Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday

ISBN-10: 0511063164

ISBN-13: 9780511063169

ISBN-10: 0511119178

ISBN-13: 9780511119170

ISBN-10: 0511545940

ISBN-13: 9780511545948

ISBN-10: 0521796520

ISBN-13: 9780521796521

This up to date and accelerated new version takes complete account of contemporary advancements and conveys the fundamental technological know-how underlying a variety of scientific stipulations together with atherosclerosis, high blood pressure, diabetes, and being pregnant. As with the 1st version, the e-book presents an introductory account of vascular biology prior to top directly to clarify mechanisms fascinated with ailment strategies. The breadth and diversity of matters coated during this re-creation do complete justice to this more and more very important sector of medical learn and drugs. This multidisciplinary method will swimsuit the desires of all these looking to refresh their wisdom with the very most modern advances from uncomplicated technology via to scientific perform

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Additional info for An introduction to vascular biology : from basic science to clinical practice

Sample text

An alternative method for determining arterial compliance/distensibility is to measure PWV. PWV is the velocity with which the pressure pulse propagates along an artery and is inversely related to the square root of arterial distensibility (Bramwell and Hill, 1922). PWV can be determined by measuring the time delay ( T) between the foot of velocity or pressure waveforms measured at two accessible sites in the arterial tree, such as the carotid and femoral arteries. Carotid to femoral PWV (PWVcf) is given by: PWVcf = Lcf/ T where Lcf is the diVerence in length from the aortic root to the carotid artery and the length from the aortic root to the femoral artery and is estimated from surface markings.

A. G. (1995). Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in diVerentiated contractile vascular cells. Circ. , 6, 1101–18. , Amano, M. et al. (1996). Regulation of myosin phosphatase by Rho and Rho-associated kinase (rho-kinase). Science, 273, 245–8. Klockner, U. (1993). Intracellular calcium ions activate a low-conductance chloride channel in 30 A. D. Hughes smooth-muscle cells isolated from human mesenteric artery. , 424, 231–7. J. et al. (1998). p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.

Gen. , 32, 403–11. E. A. (1997). RGDN peptide interaction with endothelial alpha5beta1 integrin causes sustained endothelin-dependent vasoconstriction of rat skeletal muscle arterioles. J. Clin. , 100, 1647–53. D. et al. (1993). Coupling of the Na+/Ca2+ exchanger, Na+/K+ pump and sarcoplasmic reticulum in smooth muscle. Nature, 365, 657–60. G. D. (1998). PKC-dependent signalling mechanisms in diVerentiated smooth muscle. Acta Physiol. , 164, 495–505. J. C. (1999). Physiological regulation of G protein-linked signaling.

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An introduction to vascular biology : from basic science to clinical practice by Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday


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